[KD Validated] MT2A Polyclonal Antibody (CAB22103)
- SKU:
- CAB22103
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | [KD Validated] MT2A Polyclonal Antibody |
SKU: | CAB22103 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-61 of human MT2A (NP_005944.1). |
Sequence: | MDPN CSCA AGDS CTCA GSCK CKEC KCTS CKKS CCSC CPVG CAKC AQGC ICKG ASDK CSCC A |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | MT2; MT-2; MT-II; [KD Validated] MT2A |
Positive Sample: | 293T,U-2 OS,U-87MG,Mouse liver,Mouse testis,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, nucleus |
Calculated MW: | 6kDa |
Observed MW: | 15kDa |
This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions, altering the intracellular concentration of heavy metals in the cell. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. The encoded protein interacts with the protein encoded by the homeobox containing 1 gene in some cell types, controlling intracellular zinc levels, affecting apoptotic and autophagy pathways. Some polymorphisms in this gene are associated with an increased risk of cancer.
Purification Method: | Affinity purification |
Gene ID: | 4502 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |