The KD Validated MIF Polyclonal Antibody is designed for research involving Macrophage Migration Inhibitory Factor (MIF), a key cytokine involved in inflammation and immune regulation. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in various applications including Western blot and Immunofluorescence. It binds specifically to MIF, allowing for accurate detection and analysis in a variety of cell types.
MIF is known for its role in various inflammatory diseases, autoimmune disorders, and cancer progression. Understanding the function and regulation of MIF is crucial for developing targeted therapies in these areas. The KD Validated MIF Polyclonal Antibody is a valuable tool for researchers studying the role of MIF in disease pathogenesis and immune response modulation.
This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways.
Purification Method:
Affinity purification
Gene ID:
4282
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using [KD Validated] MIF Rabbit pAb (CAB22682) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.