[KD Validated] MAD1/MAD1L1 Polyclonal Antibody (CAB22000)
- SKU:
- CAB22000
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | [KD Validated] MAD1/MAD1L1 Polyclonal Antibody |
SKU: | CAB22000 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 351-718 of human MAD1/MAD1L1 (NP_003541.2). |
Sequence: | KNSA VTSS ARGL EKAR QQLQ EELR QVSG QLLE ERKK RETH EALA RRLQ KRVL LLTK ERDG MRAI LGSY DSEL TPAE YSPQ LTRR MREA EDMV QKVH SHSA EMEA QLSQ ALEE LGGQ KQRA DMLE MELK MLKS QSSS AEQS FLFS REEA DTLR LKVE ELEG ERSR LEEE KRML EAQL ERRA LQGD YDQS RTKV LHMS LNPT SVAR QRLR EDHS QLQA ECER LRGL LRAM ERGG TVPA DLEA AAAS LPSS KEVA ELKK QVES AELK NQRL KEVF QTKI QEFR KACY TLTG YQID ITTE NQYR LTSL YAEH PGDC LIFK ATSP SGSK MQLL ETEF SHTV GELI EVHL RRQD SIPA FLSS LTLE LFSR QTVA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | MAD1; MVA7; PIG9; TP53I9; TXBP181; [KD Validated] MAD1/MAD1L1 |
Positive Sample: | 293T,HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | centrosome, cytoplasm, cytosol, mitotic spindle, mitotic spindle assembly checkpoint MAD1-MAD2 complex, nuclear pore nuclear basket, nucleus, spindle, spindle pole |
Calculated MW: | 83kDa |
Observed MW: | 83kDa |
MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 8379 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |