The IL13 Monoclonal Antibody (MAB10003) offered by AssayGenie is a reliable tool for researchers studying IL13, a cytokine involved in inflammatory and immune responses. This antibody, produced using hybridoma technology, is specifically designed to target and detect IL13 in various samples, including human tissues and cells. IL13 is known for its role in promoting allergic responses and inflammation, making it a key player in conditions such as asthma and allergy-related diseases. By targeting IL13 with this monoclonal antibody, researchers can accurately measure levels of IL13, analyze its function, and potentially develop therapeutic strategies to modulate its activity.
With its high specificity and sensitivity in techniques such as Western blot and immunohistochemistry, the IL13 Monoclonal Antibody is a valuable tool for advancing research in immunology, allergy, and inflammatory diseases. By understanding the impact of IL13 on immune regulation, researchers can uncover new insights into disease mechanisms and develop targeted treatments for patients in need.
Product Name:
[KD Validated] IL13 Monoclonal Antibody
SKU:
CAB23415
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant protein of human IL13.
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:1000
Synonyms:
P600; IL-13; [KD Validated] IL13
Positive Sample:
MCF7
Conjugate:
Unconjugated
Cellular Localization:
Secreted.
Calculated MW:
16kDa
Observed MW:
16kDa
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.
Purification Method:
Affinity purification
Gene ID:
3596
Clone Number:
ARC61007
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type(WT) and IL13 knockdown (KD) MCF7 cells, using [KD Validated] IL13 Rabbit mAb (CAB23415) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
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