The GPLD1 Polyclonal Antibody (ABIN535377) is a valuable tool for researchers studying GPLD1, a glycoprotein that plays a crucial role in lipid metabolism and immune response regulation. This antibody, generated in rabbits, demonstrates high specificity and sensitivity in detecting GPLD1 in human samples, making it ideal for use in Western blot and immunohistochemistry applications.GPLD1, also known as phosphatidylglycerophosphatase, is involved in the hydrolysis of glycerophospholipids, contributing to the regulation of lipid levels and immune cell function. Dysregulation of GPLD1 has been implicated in various diseases, including lipid metabolism disorders, immune-related conditions, and certain cancers.
By targeting GPLD1 with this polyclonal antibody, researchers can gain insights into its role in these disease processes and explore its potential as a therapeutic target. The validation of this antibody in Western blot applications ensures reliable and reproducible results for experiments investigating GPLD1 expression and function in different cell types and tissues. With its versatility and proven performance, the GPLD1 Polyclonal Antibody is a valuable asset for studies in lipid biology, immunology, and disease mechanisms.
Product Name:
[KD Validated] GPLD1 Polyclonal Antibody
SKU:
CAB21781
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-160 of human GPLD1 (NP_001494.2).
Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane.
Purification Method:
Affinity purification
Gene ID:
2822
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Daudi cells, using [KD Validated] GPLD1 Rabbit pAb (CAB21781) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
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