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[KD Validated] Gelsolin Polyclonal Antibody (CAB22015)

SKU:
CAB22015
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
IHC
$167 - $635
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KD Validated] Gelsolin Polyclonal Antibody
SKU:CAB22015
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 28-782 of human Gelsolin (NP_000168.1).
Sequence:ATAS RGAS QAGA PQGR VPEA RPNS MVVE HPEF LKAG KEPG LQIW RVEK FDLV PVPT NLYG DFFT GDAY VILK TVQL RNGN LQYD LHYW LGNE CSQD ESGA AAIF TVQL DDYL NGRA VQHR EVQG FESA TFLG YFKS GLKY KKGG VASG FKHV VPNE VVVQ RLFQ VKGR RVVR ATEV PVSW ESFN NGDC FILD LGNN IHQW CGSN SNRY ERLK ATQV SKGI RDNE RSGR ARVH VSEE GTEP EAML QVLG PKPA LPAG TEDT AKED AANR KLAK LYKV SNGA GTMS VSLV ADEN PFAQ GALK SEDC FILD HGKD GKIF VWKG KQAN TEER KAAL KTAS DFIT KMDY PKQT QVSV LPEG GETP LFKQ FFKN WRDP DQTD GLGL SYLS SHIA NVER VPFD AATL HTST AMAA QHGM DDDG TGQK QIWR IEGS NKVP VDPA TYGQ FYGG DSYI ILYN YRHG GRQG QIIY NWQG AQST QDEV AASA ILTA QLDE ELGG TPVQ SRVV QGKE PAHL MSLF GGKP MIIY KGGT SREG GQTA PAST RLFQ VRAN SAGA TRAV EVLP KAGA LNSN DAFV LKTP SAAY LWVG TGAS EAEK TGAQ ELLR VLRA QPVQ VAEG SEPD GFWE ALGG KAAY RTSP RLKD KKMD AHPP RLFA CSNK IGRF VIEE VPGE LMQE DLAT DDVM LLDT WDQV FVWV GKDS QEEE KTEA LTSA KRYI ETDP ANRD RRTP ITVV KQGF EPPS FVGW FLGW DDDY WSVD PLDR AMAE LAA
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:100 - 1:500 IHC-P,1:50 - 1:200
Synonyms:ADF; AGEL; [KD Validated] Gelsolin
Positive Sample:HeLa,HepG2,C2C12
Cellular Localization:actin cytoskeleton, blood microparticle, cortical actin cytoskeleton, cytoplasm, cytosol, extracellular exosome, extracellular region, extracellular space, focal adhesion, phagocytic vesicle, plasma membrane, podosome
Calculated MW:86kDa
Observed MW:86kDa

The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:2934
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from HepG2 cells, using [KD Validated] Gelsolin Rabbit pAb (CAB22015) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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