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[KD Validated] EIF2AK1 Monoclonal Antibody

SKU:
CAB24614
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
€139 - €529
Frequently bought together:

Description

[KD Validated] EIF2AK1 Monoclonal Antibody (CAB24614)

The EIF2AK1 Monoclonal Antibody is a key tool for researchers studying EIF2AK1, a protein involved in the regulation of stress-induced cell responses. This antibody, produced through monoclonal techniques, shows high specificity for EIF2AK1 and is validated for use in various experimental techniques, including Western blot and immunofluorescence.EIF2AK1, also known as eukaryotic translation initiation factor 2-alpha kinase 1, is a crucial component of the cellular stress response pathway, regulating protein synthesis in times of environmental stress.

Dysregulation of EIF2AK1 has been implicated in various diseases, including cancer, neurodegenerative disorders, and metabolic diseases. By using the EIF2AK1 Monoclonal Antibody, researchers can investigate the role of this protein in disease pathogenesis and potentially identify new therapeutic targets for intervention.

Product Name:[KD Validated] EIF2AK1 Monoclonal Antibody
Product Code:CAB24614
Reactivity:Human
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC62929
Reactivity:Human
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:1000-1:5000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:293T(KD)
Cellular Location:Cytoplasm

The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 337-586 of human EIF2AK1(NNP_055228.2).
Sequence:SIVEQ QLPLR RNSHL EESFT STEES SEENV NFLGQ TEAQY HLMLH IQMQL CELSL WDWIV ERNKR GREYV DESAC PYVMA NVATK IFQEL VEGVF YIHNM GIVHR DLKPR NIFLH GPDQQ VKIGD FGLAC TDILQ KNTDW TNRNG KRTPT HTSRV GTCLY ASPEQ LEGSE YDAKS DMYSL GVVLL ELFQP FGTEM ERAEV LTGLR TGQLP ESLRK RCPVQ AKYIQ HLTRR NSSQR PSAIQ LLQSE LFQNS
Synonyms:HCR, HRI, hHRI, LEMSPAD
Calculated MW:71kDa
Observed MW:71kDa

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