The KCTD7 Monoclonal Antibody (PACO07434) is a valuable tool for researchers studying KCTD7, a protein involved in various cellular processes, including cell cycle regulation and neuronal development. This antibody, produced through hybridoma technology, exhibits high specificity and sensitivity for KCTD7 in human samples, making it ideal for applications such as Western blot and immunofluorescence.KCTD7, a member of the potassium channel tetramerization domain (KCTD) family, has been implicated in neurological disorders and cancer progression.
Its role in modulating protein degradation and gene expression makes it a potential target for therapeutic interventions in these diseases. By utilizing the KCTD7 Monoclonal Antibody, researchers can further investigate the mechanisms by which KCTD7 influences cellular functions, shedding light on potential therapeutic strategies for related conditions.
Antibody Name:
KCTD7 Antibody (PACO07434)
Antibody SKU:
PACO07434
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:10000-1:20000, WB:1:500-1:2000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthesized peptide derived from human KCTD7. at AA range: 181-230
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western Blot analysis of 1,mouse-brain 2,mouse-spleen cells using primary antibody diluted at 1:1000(4°C overnight). Secondary antibody:Goat Anti-rabbit IgG IRDye 800( diluted at 1:5000, 25°C, 1 hour).
Synonyms:
BTB/POZ domain-containing protein KCTD7
UniProt Protein Function:
KCTD7: contains a K+ channel tetramerisation domain (T1) found in voltage-gated K+ channel proteins. Encodes molecular determinants for the assembly of functional tetrameric channels. Two alternatively spliced isoforms have been described.Protein type: Unknown functionChromosomal Location of Human Ortholog: 7q11.21Disease: Epilepsy, Progressive Myoclonic 3, With Or Without Intracellular Inclusions
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the potassium channel tetramerization domain-containing protein family. Family members are identified on a structural basis and contain an amino-terminal domain similar to the T1 domain present in the voltage-gated potassium channel. Mutations in this gene have been associated with progressive myoclonic epilepsy-3. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2011]
