The KCNK9 Polyclonal Antibody (CAB8609) is a valuable tool for researchers studying KCNK9, a potassium channel protein involved in various physiological processes, including cell excitability and neurotransmitter release. This antibody, produced in rabbits, exhibits high specificity and reactivity towards human samples, making it suitable for use in Western blot applications.KCNK9, also known as TASK-3, plays a crucial role in regulating potassium ion transport and membrane potential in cells. Dysregulation of KCNK9 has been implicated in neurological disorders, such as epilepsy and chronic pain conditions.
Therefore, studying the expression and function of KCNK9 is essential for gaining insights into these diseases and developing potential therapeutic strategies.With the ability to detect and analyze KCNK9 protein in different cell types, the KCNK9 Polyclonal Antibody is an excellent tool for researchers exploring the role of potassium channels in various physiological and pathological conditions, including neurobiology and pain research. By understanding the mechanisms underlying KCNK9 function, researchers can pave the way for novel therapeutic interventions targeting potassium channel dysfunction.
Product Name:
KCNK9 Rabbit Polyclonal Antibody
SKU:
CAB8609
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human KCNK9 (NP_001269463.1).
This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel. Amplification and overexpression of this gene have been observed in several types of human carcinomas. This gene is imprinted in the brain, with preferential expression from the maternal allele. A mutation in this gene was associated with Birk-Barel dysmorphism syndrome. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
51305
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using KCNK9 antibody (CAB8609) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 15s.
