The KCNK6 Polyclonal Antibody (CAB16087) is a valuable tool for researchers studying the KCNK6 gene, which encodes a two-pore domain potassium channel known to be involved in regulating cell membrane potential and ion transport. This antibody, produced in rabbits, has high specificity for human samples and has been validated for use in Western blot applications. By binding to the KCNK6 protein, this antibody enables researchers to detect and analyze its expression in various cell types.The KCNK6 gene is of particular interest in the fields of neuroscience and cardiovascular research due to its role in controlling the excitability of neurons and cardiac muscle cells.
Dysregulation of KCNK6 activity has been linked to conditions such as epilepsy, arrhythmias, and hypertension, making it a promising target for therapeutic intervention.By using the KCNK6 Polyclonal Antibody, researchers can gain valuable insights into the function of this potassium channel and its potential implications in disease states. This antibody is essential for studies aimed at unraveling the molecular mechanisms underlying neurological and cardiovascular disorders, paving the way for the development of novel treatments to address these conditions.
Product Name:
KCNK6 Rabbit Polyclonal Antibody
SKU:
CAB16087
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 254-313 of human KCNK6 (NP_004814.1).
This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. This channel protein, considered an open rectifier, is widely expressed. It is stimulated by arachidonic acid, and inhibited by internal acidification and volatile anaesthetics.
Purification Method:
Affinity purification
Gene ID:
9424
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KCNK6 Rabbit pAb (CAB16087) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
