The KCNJ5 Polyclonal Antibody (CAB6232) is a valuable tool for researchers studying the KCNJ5 protein, which is involved in regulating potassium channels in cells. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the KCNJ5 protein, this antibody enables the detection and analysis of KCNJ5 in various cell types, making it ideal for studies in physiology, pharmacology, and neuroscience.The KCNJ5 protein is a potassium channel subunit that plays a crucial role in maintaining the electrical activity of cells, making it essential for proper cell function.
Dysregulation of KCNJ5 has been associated with various diseases, including cardiac arrhythmias and neurological disorders. Therefore, understanding the function and regulation of KCNJ5 is essential for developing potential therapies targeting these conditions.Overall, the KCNJ5 Polyclonal Antibody is a valuable tool for researchers investigating the role of the KCNJ5 protein in cellular function and disease pathogenesis. By enabling precise detection and analysis of KCNJ5, this antibody contributes to advancements in the fields of physiology, pharmacology, and neuroscience.
Product Name:
KCNJ5 Rabbit Polyclonal Antibody
SKU:
CAB6232
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human KCNJ5 (NP_000881.3).
This gene encodes an integral membrane protein which belongs to one of seven subfamilies of inward-rectifier potassium channel proteins called potassium channel subfamily J. The encoded protein is a subunit of the potassium channel which is homotetrameric. It is controlled by G-proteins and has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Naturally occurring mutations in this gene are associated with aldosterone-producing adenomas.
Purification Method:
Affinity purification
Gene ID:
3762
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using KCNJ5 Antibody (CAB6232) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
