KCNJ4 Rabbit Polyclonal Antibody (CAB14010)
- SKU:
- CAB14010
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
Product Name: | KCNJ4 Rabbit Polyclonal Antibody |
SKU: | CAB14010 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human KCNJ4 (NP_004972.1). |
Sequence: | CVDT RWRY MLMI FSAA FLVS WLFF GLLF WCIA FFHG DLEA SPGV PAAG GPAA GGGG AAPV APKP CIMH VNGF LGAF LFSV ETQT TIGY GFRC VTEE CPLA V |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | HIR; HRK1; IRK3; HIRK2; IRK-3; Kir2.3; KCNJ4 |
Positive Sample: | SKOV3,Mouse skeletal muscle,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cytoplasmic vesicle membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse. |
Calculated MW: | 50kDa |
Observed MW: | 49kDa |
Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 3761 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |