The KCNIP2 Polyclonal Antibody (CAB7100) is specifically designed for researchers looking to study KCNIP2, a member of the Kv channel interacting protein (KChIP) family that plays a crucial role in the regulation of potassium channels in the brain. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.KCNIP2 is known for its involvement in various neurological processes, including synaptic plasticity and neuronal excitability. By targeting the KCNIP2 protein, this antibody enables the detection and analysis of KCNIP2 expression in different cell types, making it a valuable tool for studies in neurobiology and neuroscience.
With its ability to specifically recognize KCNIP2, researchers can gain insights into the functions and mechanisms underlying potassium channel regulation in the brain. This antibody is essential for investigating the role of KCNIP2 in neurological disorders and diseases, providing valuable information for the development of potential therapeutic interventions targeting potassium channel dysfunction.
Product Name:
KCNIP2 Rabbit Polyclonal Antibody
SKU:
CAB7100
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human KCNIP2 (NP_775284.1).
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified from this gene.
Purification Method:
Affinity purification
Gene ID:
30819
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using KCNIP2 antibody (CAB7100) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
