The KCNH7 Polyclonal Antibody (CAB15923) is a vital tool for researchers studying the KCNH7 gene, which codes for a potassium voltage-gated channel subfamily H member 7 protein. This antibody, generated in rabbits, is highly specific for detecting KCNH7 protein expression in human samples and is validated for use in Western blot applications.The KCNH7 protein plays a crucial role in regulating ion channels in various cell types, making it an important target for research in neuroscience, cardiology, and pharmacology. By targeting the KCNH7 protein, researchers can gain insights into the mechanisms underlying potassium channel function and its impact on cellular physiology.
The KCNH7 Polyclonal Antibody is a valuable tool for investigating the role of KCNH7 in neurological disorders, cardiac arrhythmias, and drug discovery efforts aimed at modulating potassium channel activity. Its high specificity and sensitivity make it a key component in advancing our understanding of potassium channel biology and its implications for human health.
Product Name:
KCNH7 Rabbit Polyclonal Antibody
SKU:
CAB15923
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 100-350 of human KCNH7 (NP_775185.1).
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms.
Purification Method:
Affinity purification
Gene ID:
90134
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse brain, using KCNH7 Rabbit pAb (CAB15923) at 1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
