KCNH1 Rabbit Polyclonal Antibody (CAB6636)
- SKU:
- CAB6636
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
Product Name: | KCNH1 Rabbit Polyclonal Antibody |
SKU: | CAB6636 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 813-962 of human KCNH1 (NP_002229.1). |
Sequence: | FKDA CGKS EDWN KVSK AESM ETLP ERTK ASGE ATLK KTDS CDSG ITKS DLRL DNVG EARS PQDR SPIL AEVK HSFY PIPE QTLQ ATVL EVRH ELKE DIKA LNAK MTNI EKQL SEIL RILT SRRS SQSP QELF EISR PQSP ESER DIFG AS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | EAG; EAG1; ZLS1; hEAG; TMBTS; h-eag; hEAG1; Kv10.1; KCNH1 |
Positive Sample: | Raji,MCF7,HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Early endosome membrane, Multi-pass membrane protein, Nucleus inner membrane. |
Calculated MW: | 111kDa |
Observed MW: | 111kDa |
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms.
Purification Method: | Affinity purification |
Gene ID: | 3756 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |