The KCNG4 Polyclonal Antibody (CAB14435) is a valuable tool for researchers studying the KCNG4 gene, which encodes a voltage-gated potassium channel subunit. This antibody, generated in rabbits, is highly specific and reactive to human samples, making it suitable for use in Western blot applications.The KCNG4 protein is involved in regulating cell membrane potential and plays a crucial role in controlling the excitability of neurons and muscle cells. By targeting KCNG4 with this polyclonal antibody, researchers can accurately detect and analyze the expression of this protein in a variety of cell types, providing insights into neurological disorders and cardiac function.
Understanding the function of KCNG4 is essential for uncovering its potential role in diseases such as epilepsy, arrhythmias, and other conditions related to abnormal electrical activity in the body. With the KCNG4 Polyclonal Antibody, researchers can delve deeper into the mechanisms underlying these diseases and pave the way for the development of novel therapeutic strategies.
Product Name:
KCNG4 Rabbit Polyclonal Antibody
SKU:
CAB14435
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human KCNG4 (NP_758857.1).
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member functions as a modulatory subunit. The gene has strong expression in brain. Multiple alternatively spliced variants have been found in normal and cancerous tissues.
Purification Method:
Affinity purification
Gene ID:
93107
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KCNG4 Rabbit pAb (CAB14435) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
