Anti-KCNG3 Antibody (PACO19883)

Antibody Name:	KCNG3 Antibody (PACO19883)
Antibody SKU:	PACO19883
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, IHC
Recommended Dilutions:	ELISA:1:2000-1:10000, IHC:1:50-1:200
Species Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide of human KCNG3

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19883(KCNG3 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200).
	The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO19883(KCNG3 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200).

Background:

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a γ subunit functioning as a modulatory molecule. Alternative splicing results in two transcript variants encoding distinct isoforms.

Synonyms:

potassium voltage-gated channel, subfamily G, member 3

UniProt Protein Function:	KCNG3: Potassium channel subunit. Modulates channel activity. Belongs to the potassium channel family. G (TC 1.A.1.2) subfamily. Kv6.3/KCNG3 sub-subfamily. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 2p21Cellular Component: endoplasmic reticulum; plasma membrane; voltage-gated potassium channel complexMolecular Function: delayed rectifier potassium channel activity; protein binding
UniProt Protein Details:
NCBI Summary:	Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit functioning as a modulatory molecule. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
UniProt Code:	Q8TAE7
NCBI GenInfo Identifier:	24418472
NCBI Gene ID:	170850
NCBI Accession:	Q8TAE7.1
UniProt Secondary Accession:	Q8TAE7,Q53SC1
UniProt Related Accession:	Q8TAE7
Molecular Weight:	48,534 Da
NCBI Full Name:	Potassium voltage-gated channel subfamily G member 3
NCBI Synonym Full Names:	potassium voltage-gated channel modifier subfamily G member 3
NCBI Official Symbol:	KCNG3
NCBI Official Synonym Symbols:	KV6.3; KV10.1
NCBI Protein Information:	potassium voltage-gated channel subfamily G member 3
UniProt Protein Name:	Potassium voltage-gated channel subfamily G member 3
UniProt Synonym Protein Names:	Voltage-gated potassium channel subunit Kv10.1; Voltage-gated potassium channel subunit Kv6.3
Protein Family:	Potassium voltage-gated channel subfamily
UniProt Gene Name:	KCNG3
UniProt Entry Name:	KCNG3_HUMAN

Antibodies

KCNG3 Antibody (PACO02583)

KCNG3 Antibody (PACO07192)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)