Anti-KCNG2 Antibody (PACO19880)

Antibody Name:	KCNG2 Antibody (PACO19880)
Antibody SKU:	PACO19880
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:50-1:200
Species Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide of human KCNG2

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19880(KCNG2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200).
	Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse brain tissue, Primary antibody: PACO19880(KCNG2 Antibody) at dilution 1/650, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes.
	The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO19880(KCNG2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200).

Background:

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a γ subunit of the voltage-gated potassium channel. The delayed-rectifier type channels containing this subunit may contribute to cardiac action potential repolarization.

Synonyms:

potassium voltage-gated channel, subfamily G, member 2

UniProt Protein Function:	Kv6.2: Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values. Belongs to the potassium channel family. G (TC 1.A.1.2) subfamily. Kv6.2/KCNG2 sub-subfamily.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 18q23Cellular Component: plasma membraneMolecular Function: delayed rectifier potassium channel activityBiological Process: potassium ion transport; regulation of heart contraction; regulation of insulin secretion
UniProt Protein Details:
NCBI Summary:	Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit of the voltage-gated potassium channel. The delayed-rectifier type channels containing this subunit may contribute to cardiac action potential repolarization. [provided by RefSeq, Jul 2008]
UniProt Code:	Q9UJ96
NCBI GenInfo Identifier:	24418480
NCBI Gene ID:	26251
NCBI Accession:	Q9UJ96.1
UniProt Secondary Accession:	Q9UJ96
UniProt Related Accession:	Q9UJ96
Molecular Weight:	51,240 Da
NCBI Full Name:	Potassium voltage-gated channel subfamily G member 2
NCBI Synonym Full Names:	potassium voltage-gated channel modifier subfamily G member 2
NCBI Official Symbol:	KCNG2
NCBI Official Synonym Symbols:	KCNF2; KV6.2
NCBI Protein Information:	potassium voltage-gated channel subfamily G member 2
UniProt Protein Name:	Potassium voltage-gated channel subfamily G member 2
UniProt Synonym Protein Names:	Cardiac potassium channel subunit; Voltage-gated potassium channel subunit Kv6.2
Protein Family:	Potassium voltage-gated channel subfamily
UniProt Gene Name:	KCNG2
UniProt Entry Name:	KCNG2_HUMAN

Antibodies

KCNG2 Antibody (PACO00993)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)