The KCNE1 Polyclonal Antibody (CAB1176) is a valuable tool for research focusing on the KCNE1 protein, which is known for its role in cardiac ion channel regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.KCNE1 plays a crucial role in modulating potassium ion channels in the heart, impacting the cardiac action potential and electrical conduction. Dysregulation of KCNE1 has been linked to various cardiac arrhythmias and other cardiovascular conditions. By targeting the KCNE1 protein, researchers can gain insights into the mechanisms underlying these pathologies and potentially develop new therapeutic strategies.
With its ability to specifically bind to KCNE1, this polyclonal antibody enables accurate detection and analysis of the protein in different cell types and tissues. Its application in studies related to cardiac physiology and pathology makes it a valuable asset for researchers in the fields of cardiology, electrophysiology, and drug discovery. Gain a deeper understanding of KCNE1 function and its implications in cardiovascular health using the KCNE1 Polyclonal Antibody (CAB1176).
Product Name:
KCNE1 Rabbit Polyclonal Antibody
SKU:
CAB1176
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human KCNE1 (NP_000210.2).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
15kDa
Observed MW:
16kDa
The product of this gene belongs to the potassium channel KCNE family. Potassium ion channels are essential to many cellular functions and show a high degree of diversity, varying in their electrophysiologic and pharmacologic properties. This gene encodes a transmembrane protein known to associate with the product of the KVLQT1 gene to form the delayed rectifier potassium channel. Mutation in this gene are associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome. Alternatively spliced transcript variants encoding the same protein have been identified.
Purification Method:
Affinity purification
Gene ID:
3753
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using KCNE1 antibody (CAB1176) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
