KCND3 Rabbit Polyclonal Antibody (CAB6927)
- SKU:
- CAB6927
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
Product Name: | KCND3 Rabbit Polyclonal Antibody |
SKU: | CAB6927 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 521-655 of human KCND3 (NP_004971.2). |
Sequence: | MESS MQNY PSTR SPSL SSHP GLTT TCCS RRSK KTTH LPNS NLPA TRLR SMQE LSTI HIQG SEQP SLTT SRSS LNLK ADDG LRPN CKTS QITT AIIS IPTP PALT PEGE SRPP PASP GPNT NIPS IASN VVKV SAL |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 |
Synonyms: | KV4.3; SCA19; SCA22; BRGDA9; KCND3L; KCND3S; KSHIVB; KCND3 |
Positive Sample: | A-549,SH-SY5Y,Mouse heart,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cell projection, Membrane, Multi-pass membrane protein, dendrite, sarcolemma. |
Calculated MW: | 73kDa |
Observed MW: | 73kDa |
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene.
Purification Method: | Affinity purification |
Gene ID: | 3752 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |