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KCND3 Rabbit Polyclonal Antibody (CAB6927)

SKU:
CAB6927
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
  • Signal Transduction Antibodies 3 Anti-KCND3 Antibody CAB6927
  • Signal Transduction Antibodies 3 Anti-KCND3 Antibody CAB6927
€139 - €419
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Description

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KCND3 Rabbit Polyclonal Antibody (CAB6927)

The KCND3 Polyclonal Antibody (CAB6927) is a vital tool for researchers studying the potassium voltage-gated channel subfamily D member 3 protein, which plays a key role in regulating the flow of potassium ions in cells. This antibody, generated in rabbits, exhibits high specificity and sensitivity when detecting KCND3 in human samples, making it an excellent choice for Western blot applications.By targeting the KCND3 protein, this antibody allows for the precise detection and analysis of potassium channel activity in various cell types, providing valuable insights into the role of KCND3 in cellular function and disease processes.

With implications in areas such as neuroscience, cardiac biology, and cancer research, the KCND3 Polyclonal Antibody is an essential tool for understanding the impact of potassium channels on cellular physiology and disease progression.

Product Name:KCND3 Rabbit Polyclonal Antibody
SKU:CAB6927
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 521-655 of human KCND3 (NP_004971.2).
Sequence:MESS MQNY PSTR SPSL SSHP GLTT TCCS RRSK KTTH LPNS NLPA TRLR SMQE LSTI HIQG SEQP SLTT SRSS LNLK ADDG LRPN CKTS QITT AIIS IPTP PALT PEGE SRPP PASP GPNT NIPS IASN VVKV SAL
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:100 - 1:500 IHC-P,1:50 - 1:200
Synonyms:KV4.3; SCA19; SCA22; BRGDA9; KCND3L; KCND3S; KSHIVB; KCND3
Positive Sample:A-549,SH-SY5Y,Mouse heart,Rat heart
Conjugate:Unconjugated
Cellular Localization:Cell membrane, Cell projection, Membrane, Multi-pass membrane protein, dendrite, sarcolemma.
Calculated MW:73kDa
Observed MW:73kDa

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene.

Purification Method:Affinity purification
Gene ID:3752
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using KCND3 Rabbit pAb (CAB6927) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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