The KCNC4 Polyclonal Antibody (CAB15682) is a valuable tool for researchers studying the KCNC4 gene, which encodes a protein belonging to the voltage-gated potassium channel subfamily. This antibody, produced in rabbits, is highly specific for human samples and is suitable for use in Western blot and immunohistochemistry applications.By targeting the KCNC4 protein, this antibody allows for the detection and characterization of KCNC4 expression in various cell types and tissues.
Understanding the role of KCNC4 in cellular physiology and its implications in diseases such as epilepsy, schizophrenia, and neuropathic pain can provide valuable insights for therapeutic development in neurological and psychiatric disorders.The KCNC4 Polyclonal Antibody is a reliable tool for researchers looking to unravel the functional significance of KCNC4 in health and disease, offering a promising avenue for advancements in precision medicine and drug discovery.
Product Name:
KCNC4 Rabbit Polyclonal Antibody
SKU:
CAB15682
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 490-538 of human KCNC4 (NP_004969.2).
Sequence:
KKRK KHVP RPAQ LESP MYCK SEET SPRD STCS DTSP PARE EGMI ERKR A
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:2000
Synonyms:
KV3.4; C1orf30; KSHIIIC; HKSHIIIC; KCNC4
Positive Sample:
U-87MG,Mouse brain
Conjugate:
Unconjugated
Cellular Localization:
Membrane, Multi-pass membrane protein.
Calculated MW:
70kDa
Observed MW:
110kDa
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Multiple transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3749
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KCNC4 Rabbit pAb (CAB15682) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
