The KCNAB3 Polyclonal Antibody (CAB14822) is a valuable tool for researchers studying KCNAB3, a potassium channel accessory subunit that plays a key role in neuronal excitability and synaptic transmission. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the KCNAB3 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential component for studies in neuroscience and neurobiology.
Known for its involvement in regulating potassium channels in the brain, KCNAB3 is crucial for proper neuronal function and communication. Dysregulation of KCNAB3 has been linked to neurological disorders such as epilepsy, making it a promising target for therapeutic interventions. By delving into the intricacies of KCNAB3 activity, researchers can gain insights that may lead to advancements in the treatment of various neurological conditions.
Product Name:
KCNAB3 Rabbit Polyclonal Antibody
SKU:
CAB14822
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 285-404 of human KCNAB3 (NP_004723.2).
This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. The encoded protein is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. The encoded protein forms a heterodimer with the potassium voltage-gated channel, shaker-related subfamily, member 5 gene product and regulates the activity of the alpha subunit.
Purification Method:
Affinity purification
Gene ID:
9196
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KCNAB3 Rabbit pAb (CAB14822) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
