The KCNAB3 Polyclonal Antibody (CAB14821) is a valuable tool for researchers studying KCNAB3, a protein associated with voltage-gated potassium channels. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By targeting the KCNAB3 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal choice for investigations in the fields of neuroscience, cardiology, and ion channel physiology.KCNAB3 is a key regulatory subunit of voltage-gated potassium channels, playing a crucial role in controlling the electrical activity of cells. Dysregulation of potassium channels has been implicated in various diseases, including cardiac arrhythmias, epilepsy, and neurological disorders.
By studying the function and expression of KCNAB3, researchers can gain insights into the mechanisms underlying these conditions and potentially identify novel therapeutic targets.Overall, the KCNAB3 Polyclonal Antibody offers a valuable tool for researchers seeking to delve into the physiological and pathological roles of potassium channels and their regulatory subunits. Its specificity and sensitivity make it a reliable choice for studies aiming to unravel the complexities of ion channel function and dysfunction.
Product Name:
KCNAB3 Rabbit Polyclonal Antibody
SKU:
CAB14821
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 285-404 of human KCNAB3 (NP_004723.2).
This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. The encoded protein is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. The encoded protein forms a heterodimer with the potassium voltage-gated channel, shaker-related subfamily, member 5 gene product and regulates the activity of the alpha subunit.
Purification Method:
Affinity purification
Gene ID:
9196
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KCNAB3 Rabbit pAb (CAB14821) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
