KCNAB1 Rabbit Polyclonal Antibody (CAB15334)
- SKU:
- CAB15334
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
Product Name: | KCNAB1 Rabbit Polyclonal Antibody |
SKU: | CAB15334 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 282-401 of human KCNAB1 (NP_751891.1). |
Sequence: | CGII SGKY GNGV PESS RASL KCYQ WLKE RIVS EEGR KQQN KLKD LSPI AERL GCTL PQLA VAWC LRNE GVSS VLLG SSTP EQLI ENLG AIQV LPKM TSHV VNEI DNIL RNKP YSKK DYRS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | hKvb3; AKR6A3; KCNA1B; Kvb1.3; hKvBeta3; KV-BETA-1; KCNAB1 |
Positive Sample: | U-251MG,293T,Mouse brain,Mouse kidney,Mouse heart,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Cytoplasmic side, Membrane, Peripheral membrane protein. |
Calculated MW: | 47kDa |
Observed MW: | 45-50kDa |
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes distinct isoforms which are encoded by alternatively spliced transcript variants of this gene. Some of these isoforms are beta subunits, which form heteromultimeric complexes with alpha subunits and modulate the activity of the pore-forming alpha subunits.
Purification Method: | Affinity purification |
Gene ID: | 7881 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |