KCNA4 Rabbit Polyclonal Antibody (CAB16390)
- SKU:
- CAB16390
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
Product Name: | KCNA4 Rabbit Polyclonal Antibody |
SKU: | CAB16390 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human KCNA4 (NP_002224.1). |
Sequence: | DIFT EEVK FYQL GEEA LLKF REDE GFVR EEED RALP ENEF KKQI WLLF EYPE SSSP ARGI AIVS VLVI LISI VIFC LETL PEFR DDRD LVMA LSAG GHGG L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | HK1; HBK4; PCN2; HPCN2; HUKII; KCNA8; KV1.4; KCNA4L; MCIDDS; KCNA4 |
Positive Sample: | Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cell projection, Multi-pass membrane protein, axon. |
Calculated MW: | 73kDa |
Observed MW: | 71kDa |
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the A-type potassium current class, the members of which may be important in the regulation of the fast repolarizing phase of action potentials in heart and thus may influence the duration of cardiac action potential.
Purification Method: | Affinity purification |
Gene ID: | 3739 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |