KCNA2 Rabbit Polyclonal Antibody (CAB6295)
- SKU:
- CAB6295
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
Product Name: | KCNA2 Rabbit Polyclonal Antibody |
SKU: | CAB6295 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human KCNA2 (NP_004965.1). |
Sequence: | MTVA TGDP ADEA AALP GHPQ DTYD PEAD HECC ERVV INIS GLRF ETQL KTLA QFPE TLLG DPKK RMRY FDPL RNEY FFDR NRPS FDAI LYYY QSGG RLRR PVNV PLDI FSEE IRFY ELGE EAME MFRE DEGY IKEE ERPL PENE FQRQ VWLL FEYP ESSG PARI I |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 |
Synonyms: | HK4; MK2; HBK5; NGK1; RBK2; DEE32; HUKIV; KV1.2; EIEE32; KCNA2 |
Positive Sample: | Mouse plasma |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cell projection, Endoplasmic reticulum membrane, Membrane, Multi-pass membrane protein, axon, dendrite, lamellipodium membrane, presynaptic cell membrane, synapse, synaptosome. |
Calculated MW: | 57kDa |
Observed MW: | 60kDa |
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1.
Purification Method: | Affinity purification |
Gene ID: | 3737 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |