The KBTBD8 Polyclonal Antibody (CAB18513) is a valuable tool for researchers investigating KBTBD8, a protein involved in various cellular processes, including cell cycle regulation and protein degradation. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting KBTBD8 in human samples, making it suitable for applications such as Western blot analysis.KBTBD8 is a substrate-specific adaptor protein that plays a role in the ubiquitin-proteasome system, which regulates protein turnover and degradation within cells. Dysregulation of this system can lead to the development of various diseases, including cancer and neurodegenerative disorders.
Therefore, studying the function of KBTBD8 and its interactions with other proteins is essential for understanding these pathological conditions and developing potential therapeutic strategies.By using the KBTBD8 Polyclonal Antibody, researchers can explore the expression and localization of KBTBD8 in different cell types and tissue samples, gaining insights into its biological functions and molecular mechanisms. This antibody is a valuable resource for studies in cell biology, cancer research, and drug discovery aimed at targeting the ubiquitin-proteasome system for therapeutic interventions.
Product Name:
KBTBD8 Rabbit Polyclonal Antibody
SKU:
CAB18513
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 50-280 of human KBTBD8 (NP_115894.2).
Involved in neural crest cell development; neural crest formation; and protein monoubiquitination. Part of Cul3-RING ubiquitin ligase complex.
Purification Method:
Affinity purification
Gene ID:
84541
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat lung, using KBTBD8 Rabbit pAb (CAB18513) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
