The KBTBD6 Polyclonal Antibody (PAC048670) offered by AssayGenie is a powerful tool for researchers studying the KBTBD6 protein, a key player in cell cycle regulation and tumorigenesis. This antibody, generated in rabbits, exhibits high specificity and reactivity towards human samples, making it an ideal choice for Western blot applications.KBTBD6, a substrate-specific adaptor of the CUL3-dependent ubiquitin ligase complex, is known to play a critical role in controlling the degradation of proteins involved in cell proliferation and tumor progression.
By targeting KBTBD6 with this antibody, researchers can gain valuable insights into the mechanisms underlying cell cycle regulation and potentially identify new therapeutic targets for cancer treatment.Overall, the KBTBD6 Polyclonal Antibody from AssayGenie is a reliable tool for investigating the functions of KBTBD6 in cellular processes and its implications in cancer biology. Its high reactivity and specificity make it a valuable asset for researchers in the fields of oncology and molecular biology.
Western Blot. Positive WB detected in: Hela whole cell lysate. All lanes: KBTBD6 antibody at 3.4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 77 kDa. Observed band size: 77 kDa..
Immunofluorescent analysis of Hela cells using PACO48670 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human liver tissue using PACO48670 at dilution of 1:100.
Background:
Cul3-RING ubiquitin ligase complex
Synonyms:
Kelch repeat and BTB domain-containing protein 6, KBTBD6
UniProt Protein Function:
KBTBD6: Chromosomal Location of Human Ortholog: 13q14.11Molecular Function: protein binding
