The KBTBD3 Polyclonal Antibody (CAB16169) is a valuable tool for researchers studying KBTBD3, a protein involved in the regulation of various cellular processes. This antibody, generated in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. Its specificity for the KBTBD3 protein allows for detection and analysis in a variety of cell types, making it an essential reagent for investigations in cell biology and molecular biology.KBTBD3 is a substrate-specific adaptor of the Cullin3-dependent E3 ubiquitin ligase complex, playing a crucial role in protein degradation and turnover.
Its involvement in these processes highlights its importance in the regulation of cellular signaling pathways and protein homeostasis. Researchers studying KBTBD3 can gain valuable insights into mechanisms of protein degradation and potential therapeutic targets for diseases related to protein misfolding or accumulation.Utilizing the KBTBD3 Polyclonal Antibody in research studies can provide a deeper understanding of the functions and regulatory mechanisms of KBTBD3, ultimately contributing to advancements in drug discovery and targeted therapies for diseases involving aberrant protein degradation pathways.
Product Name:
KBTBD3 Rabbit Polyclonal Antibody
SKU:
CAB16169
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 520-612 of human KBTBD3 (NP_689646.2).
KBTBD3 (Kelch Repeat And BTB Domain Containing 3) is a Protein Coding gene. Diseases associated with KBTBD3 include Schizotypal Personality Disorder. An important paralog of this gene is KLHL24.
Purification Method:
Affinity purification
Gene ID:
143879
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KBTBD3 Rabbit pAb (CAB16169) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
