The KAT7 Polyclonal Antibody (CAB5823) is a valuable tool for researchers studying KAT7, a protein with important roles in gene regulation and epigenetic processes. This antibody, produced in rabbits, offers high specificity and sensitivity for detecting KAT7 in human samples, making it ideal for use in Western blotting and immunofluorescence applications.KAT7, also known as HBO1, is a histone acetyltransferase involved in chromatin remodeling and transcriptional activation. It plays a crucial role in regulating gene expression and cellular processes such as cell cycle progression and DNA repair.
Dysregulation of KAT7 has been implicated in various diseases, including cancer and developmental disorders, highlighting its potential as a therapeutic target.By using the KAT7 Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of KAT7 in different biological contexts. This antibody is a valuable tool for studying epigenetic mechanisms, gene expression, and cellular pathways affected by KAT7, offering new opportunities for advancing our understanding of disease mechanisms and developing targeted therapies.
Product Name:
KAT7 Rabbit Polyclonal Antibody
SKU:
CAB5823
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 55-193 of human KAT7 (NP_008998.1).
The protein encoded by this gene is part of the multimeric HBO1 complex, which possesses histone H4-specific acetyltransferase activity. This activity is required for functional replication origins and is involved in transcriptional activation of some genes. In both cases, the acetylation of histone H4 helps unfold chromatin so that the DNA can be accessed and replicated or transcribed.
Purification Method:
Affinity purification
Gene ID:
11143
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using KAT7 Rabbit pAb (CAB5823) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
