KAT6B Rabbit Polyclonal Antibody (CAB17116)
- SKU:
- CAB17116
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | KAT6B Rabbit Polyclonal Antibody |
SKU: | CAB17116 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 400-500 of human KAT6B (NP_001243398.1). |
Sequence: | DLDV FKQA QELS WEKI ECES GVED CGRY PSVI EFGK YEIQ TWYS SPYP QEYA RLPK LYLC EFCL KYMK SKNI LLRH SKKC GWFH PPAN EIYR RKDL SVFE V |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | qkf; MORF; MOZ2; GTPTS; MYST4; ZC2HC6B; querkopf; KAT6B |
Positive Sample: | 293T,HeLa,OVCAR3,Mouse heart |
Cellular Localization: | nucleoplasm, nucleus |
Calculated MW: | 231kDa |
Observed MW: | 280kDa |
The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 23522 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |