KAT6A Rabbit Polyclonal Antibody (CAB15006)
- SKU:
- CAB15006
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | KAT6A Rabbit Polyclonal Antibody |
SKU: | CAB15006 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 800-1000 of human KAT6A (NP_001092883.1). |
Sequence: | EEPQ CQER ELEI SVGK SVSH ENKE QDSY SVES EKKP EVMA PVSS TRLS KQVL PHDS LPAN SQPS RRGR WGRK NRKT QERF GDKD SKLL LEET SSAP QEQY GECG EKSE ATQE QYTE SEEQ LVAS EEQP SQDG KPDL PKRR LSEG VEPW RGQL KKSP EALK CRLT EGSE RLPR RYSE GDRA VLRG FSES SEEE EEPE SPRS S |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | MOZ; ARTHS; MRD32; MYST3; MYST-3; ZNF220; RUNXBP2; ZC2HC6A; KAT6A |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus, PML body, nucleolus, nucleoplasm. |
Calculated MW: | 225kDa |
Observed MW: | 250kDa |
This gene encodes a member of the MOZ, YBFR2, SAS2, TIP60 family of histone acetyltransferases. The protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain. It is part of a complex that acetylates lysine-9 residues in histone 3, and in addition, it acts as a co-activator for several transcription factors. Allelic variants of this gene are associated with an autosomal dominant form of cognitive disability. Chromosomal translocations of this gene are associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 7994 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |