The KAT5 Polyclonal Antibody (CAB1678) is a valuable tool for researchers studying the KAT5 protein, also known as histone acetyltransferase 5. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.KAT5 is a key regulator of gene transcription, playing a crucial role in cellular processes such as DNA repair, cell cycle progression, and apoptosis. Dysregulation of KAT5 has been linked to various diseases, including cancer and neurological disorders, making it an important target for research.
By specifically binding to the KAT5 protein, this antibody enables detection and analysis of KAT5 expression in a variety of cell types, providing valuable insights into its functions and potential therapeutic implications. Researchers in the fields of epigenetics, oncology, and neurobiology will find this antibody to be a valuable tool in their studies.
Product Name:
KAT5 Rabbit Polyclonal Antibody
SKU:
CAB1678
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 182-282 of human KAT5/Tip60 (NP_006379.2).
The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10524
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using KAT5/Tip60 Rabbit pAb (CAB1678) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
