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KAT2A Monoclonal Antibody [PAT3G13AT] (CPAB0097)

SKU:
CPAB0097
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a
Clone:
PAT3G13AT
Applications:
WB
IF
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

KAT2A Monoclonal Antibody [PAT3G13AT] (CPAB0097)

The KAT2A Polyclonal Antibody (CPAB0097) is a vital tool for researchers studying the KAT2A protein, which is involved in epigenetic regulation and gene expression. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the KAT2A protein, this antibody allows for precise detection and analysis in a variety of cell types, making it a valuable asset for studies in molecular biology and cancer research.KAT2A, also known as GCN5L2, is a histone acetyltransferase that plays a crucial role in chromatin remodeling and transcriptional regulation. Its involvement in gene expression and cellular processes makes it a key target for research in areas such as epigenetics, gene regulation, and cancer biology.

Understanding the function and activity of KAT2A can provide valuable insights into the mechanisms underlying various diseases and may lead to the development of novel therapeutic strategies.Overall, the KAT2A Polyclonal Antibody (CPAB0097) represents a powerful tool for researchers seeking to investigate the role of KAT2A in cellular processes and disease pathways. Its high specificity and sensitivity make it an ideal choice for studying the function of KAT2A in both normal and diseased states, providing valuable information for the advancement of scientific knowledge and the development of innovative treatments.

Product Name:KAT2A Antibody
Product Sku:CPAB0097
Size:5μg
Host Species:Mouse
Immunogen:Anti-human KAT2A mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human KAT2A amino acids 411-837 purified from Ecoli.
Clone:PAT3G13AT.
Reactivity:Human
Applications:Western Blot, Immunofluorescence, ELISA
Purification Method:KAT2A antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2a
Background:KAT2A (GCN5L2 or GCN5) is a histone acetyltransferase (HAT), which functions mainly as a transcriptional activator. GCN5L2 may be one of the enzymes involved in acetylation in vivo. GCN5 is expressed primarily in the embryo and newborn and is crucial for normal embryonic development. Hence, KAT2A appears to be significant for differentiation of embryonic-derived preadipocytes. GCN5 also functions as a repressor of NF-kappa-B by promoting ubiquitination of the NF-kappa-B subunit RELA in a HAT-independent manner. Loss of GCN5L2 leads to a high occurrence of apoptosis in the KAT2A mutants, which begins before the onset of morphological abnormality.
Synonyms:Histone acetyltransferase KAT2A, General control of amino acid synthesis protein 5-like 2, Histone acetyltransferase GCN5, HsGCN5, Lysine acetyltransferase 2A, STAF97, KAT2A, GCN5, GCN5L2, HGCN5, PCAF-b, MGC102791.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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