The KAP1 Rabbit Monoclonal Antibody (CAB19568) is a powerful research tool designed for the study of KAP1, a key protein involved in gene regulation and DNA repair processes. This antibody, generated in rabbits, shows high specificity and sensitivity towards human samples, making it suitable for a variety of research applications including Western blot analysis.KAP1, also known as KRAB-associated protein 1, is a transcriptional corepressor that plays a crucial role in regulating gene expression by modifying chromatin structure. Dysregulation of KAP1 has been linked to various diseases, including cancer and neurodegenerative disorders, highlighting its importance in biological processes.
By targeting KAP1 with this antibody, researchers can gain valuable insights into its function and potentially uncover new therapeutic targets for disease treatment.The versatility and reliability of the KAP1 Rabbit Monoclonal Antibody make it an essential tool for studies in molecular biology, cell biology, and disease mechanisms. Its ability to specifically detect KAP1 protein in various cell types and tissues makes it an invaluable asset for researchers aiming to elucidate the complex role of KAP1 in health and disease. Unlock the potential of your research with the KAP1 Rabbit Monoclonal Antibody (CAB19568).
Product Name:
KAP1/TRIM28 Rabbit Monoclonal Antibody
SKU:
CAB19568
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human KAP1/TRIM28 (Q13263).
The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region.
Purification Method:
Affinity purification
Gene ID:
10155
Clone Number:
ARC0047
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using KAP1/TRIM28 Rabbit mAb (CAB19568) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
