The KANK2 Polyclonal Antibody (CAB15420) is a valuable tool for researchers studying the KANK2 protein, a key regulator of cell migration and cytoskeletal dynamics. This antibody, produced in rabbits, exhibits high specificity and sensitivity when working with human samples, and has been validated for use in Western blot applications.KANK2 is known to play a critical role in various cellular processes, including cell adhesion, proliferation, and motility. Its dysregulation has been linked to cancer progression and metastasis, making it a promising target for cancer research.
By targeting the KANK2 protein, researchers can gain insights into the mechanisms underlying tumor growth and invasion, leading to the development of novel therapeutic strategies.Overall, the KANK2 Polyclonal Antibody is a valuable tool for studies in cell biology and cancer research, allowing for the detection and analysis of KANK2 protein levels in a variety of cell types. Its versatility and reliability make it an essential component of any laboratory focused on understanding the molecular mechanisms driving disease progression.
Product Name:
KANK2 Rabbit Polyclonal Antibody
SKU:
CAB15420
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human KANK2 (NP_001129663.1).
This gene encodes a member of the KN motif and ankyrin repeat domains (KANK) family of proteins, which play a role in cytoskeletal formation by regulating actin polymerization. The encoded protein functions in the sequestration of steroid receptor coactivators and possibly other proteins. Mutations in this gene are associated with impaired kidney podocyte function and nephrotic syndrome, and keratoderma and woolly hair.
Purification Method:
Affinity purification
Gene ID:
25959
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KANK2 Rabbit pAb (CAB15420) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
