The KANK1 Rabbit Polyclonal Antibody (CAB17106) is a valuable tool for researchers studying the KANK1 protein, which is involved in various cellular processes such as cell migration, adhesion, and cytoskeletal organization. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for Western blotting applications.KANK1 plays a crucial role in regulating actin dynamics and cell morphology, making it a potential target for studies on cancer metastasis, cell motility, and cytoskeletal rearrangements.
By targeting the KANK1 protein, researchers can gain insights into its functions in different cell types, aiding in the investigation of its roles in disease mechanisms and potential therapeutic strategies.Overall, the KANK1 Rabbit Polyclonal Antibody (CAB17106) offers researchers a reliable tool for studying the essential functions of the KANK1 protein in various biological contexts, contributing to advancements in cell biology, cancer research, and drug development.
Product Name:
KANK1 Rabbit Polyclonal Antibody
SKU:
CAB17106
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 900-1000 of human KANK1 (NP_055973.2).
The protein encoded by this gene belongs to the Kank family of proteins, which contain multiple ankyrin repeat domains. This family member functions in cytoskeleton formation by regulating actin polymerization. This gene is a candidate tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder. A t(5;9) translocation results in fusion of the platelet-derived growth factor receptor beta gene (PDGFRB) on chromosome 5 with this gene in a myeloproliferative neoplasm featuring severe thrombocythemia. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 20.
Purification Method:
Affinity purification
Gene ID:
23189
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunofluorescence analysis of L929 cells using KANK1 Rabbit pAb (CAB17106) at dilution of 1:100. Blue: DAPI for nuclear staining.
