KANK1 Rabbit Polyclonal Antibody (CAB17106)
- SKU:
- CAB17106
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | KANK1 Rabbit Polyclonal Antibody |
SKU: | CAB17106 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 900-1000 of human KANK1 (NP_055973.2). |
Sequence: | GNYL GYTC KCGG LQSG SPLS SQTS QPEQ EVGT SEGK PISS LDAF PTQE GTLS PVNL TDDQ IAAG LYAC TNNE STLK SIMK KKDG NKDS NGAK KNLQ FVGI N |
Tested Applications: | IF/ICC ELISA |
Recommended Dilution: | IF/ICC,1:50 - 1:200 |
Synonyms: | KANK; CPSQ2; ANKRD15; KANK1 |
Cellular Localization: | cytoplasm, cytoskeleton, nucleus, plasma membrane, ruffle membrane |
Calculated MW: | 147kDa |
Observed MW: | Refer to figures |
The protein encoded by this gene belongs to the Kank family of proteins, which contain multiple ankyrin repeat domains. This family member functions in cytoskeleton formation by regulating actin polymerization. This gene is a candidate tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder. A t(5;9) translocation results in fusion of the platelet-derived growth factor receptor beta gene (PDGFRB) on chromosome 5 with this gene in a myeloproliferative neoplasm featuring severe thrombocythemia. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 20.
Purification Method: | Affinity purification |
Gene ID: | 23189 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |