KALRN Antibody (PACO05661)
- SKU:
- PACO05661
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | KALRN Antibody (PACO05661) |
| Antibody SKU: | PACO05661 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:20000, WB:1:500-1:2000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from the Internal region of human Duo. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | KALRN; DUET; DUO; HAPIP; TRAD; Kalirin; Huntingtin-associated protein-interacting protein; Protein Duo; Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain |
| UniProt Protein Function: | Promotes the exchange of GDP by GTP. Activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, through their effects on the actin cytoskeleton. Induces lamellipodia independent of its GEF activity. |
| UniProt Protein Details: | |
| NCBI Summary: | Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. [provided by RefSeq, Apr 2016] |
| UniProt Code: | O60229 |
| NCBI GenInfo Identifier: | 34785972 |
| NCBI Gene ID: | 8997 |
| NCBI Accession: | AAH58015.1 |
| UniProt Secondary Accession: | O60229 |
| UniProt Related Accession: | O60229 |
| Molecular Weight: | |
| NCBI Full Name: | KALRN protein, partial |
| NCBI Synonym Full Names: | kalirin RhoGEF kinase |
| NCBI Official Symbol: | KALRNÂ Â |
| NCBI Official Synonym Symbols: | DUO; CHD5; DUET; TRAD; CHDS5; HAPIP; ARHGEF24Â Â |
| NCBI Protein Information: | kalirin |
| UniProt Protein Name: | Kalirin |
| UniProt Synonym Protein Names: | Huntingtin-associated protein-interacting protein; Protein Duo; Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain |
| Protein Family: | Duodenase |
| UniProt Gene Name: | KALRNÂ Â |
| UniProt Entry Name: |
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