KLK6 Rabbit Polyclonal Antibody (CAB12055)
- SKU:
- CAB12055
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | KLK6 Rabbit Polyclonal Antibody |
SKU: | CAB12055 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human KLK6 (NP_002765.1). |
Sequence: | AASH DQDI MLLR LARP AKLS ELIQ PLPL ERDC SANT TSCH ILGW GKTA DGDF PDTI QCAY IHLV SREE CEHA YPGQ ITQN MLCA GDEK YGKD SCQG DSGG PLVC GDHL RGLV SWGN IPCG SKEK PGVY TNVC RYTN WIQK TIQA K |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | hK6; Bssp; Klk7; SP59; PRSS9; PRSS18; KLK6 |
Positive Sample: | HT-29 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Microsome, Mitochondrion, Nucleus, Secreted, nucleolus. |
Calculated MW: | 26kDa |
Observed MW: | 27kDa |
This gene encodes a member of the kallikrein subfamily of the peptidase S1 family of serine proteases. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The encoded preproprotein is proteolytically processed to generate the mature protease. Expression of this protease is regulated by steroid hormones and may be elevated in multiple human cancers and in serum from psoriasis patients. The encoded protease may participate in the cleavage of amyloid precursor protein and alpha-synuclein, thus implicating this protease in Alzheimer's and Parkinson's disease, respectively. This gene is located in a gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Purification Method: | Affinity purification |
Gene ID: | 5653 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |