The Kallikrein 4 Polyclonal Antibody (CAB6642) is a vital tool for researchers studying Kallikrein 4, a member of the kallikrein-related peptidase family known for its involvement in various physiological processes, including tissue remodeling and cancer progression. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for use in Western blot experiments.By targeting the Kallikrein 4 protein, this antibody allows for the accurate detection and analysis of Kallikrein 4 expression in a variety of cell types, facilitating research in fields such as oncology and biomarker discovery.
Kallikrein 4 has been implicated in several malignancies, making it a promising candidate for the development of diagnostic and therapeutic strategies in cancer treatment.The unique properties of the Kallikrein 4 Polyclonal Antibody make it an invaluable tool for researchers aiming to unravel the intricate role of Kallikrein 4 in cancer biology and other diseases, ultimately paving the way for the development of novel interventions and personalized medicine approaches.
Product Name:
KLK4 Rabbit Polyclonal Antibody
SKU:
CAB6642
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-254 of human KLK4 (NP_004908.4).
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In some tissues its expression is hormonally regulated. The expression pattern of a similar mouse protein in murine developing teeth supports a role for the protein in the degradation of enamel proteins. Several transcript variants encoding different proteins have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
9622
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using KLK4 Antibody (CAB6642) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
