The Kallikrein 15 Polyclonal Antibody (CAB2757) is a vital tool for researchers studying the Kallikrein 15 protein, which is involved in various physiological processes including tissue injury and repair, inflammation, and cancer progression. This rabbit-derived antibody is highly specific for human samples and has been validated for use in Western blot applications.Kallikrein 15, also known as PRSS9, is a serine protease that plays a significant role in proteolytic cascades, particularly in the kallikrein-kinin system. Its dysregulation has been linked to various diseases including cancer, making it a promising target for therapeutic interventions.
The Kallikrein 15 Polyclonal Antibody enables precise detection and analysis of the protein in different cell types, facilitating research in oncology and inflammation-related disorders.Understanding the function and regulation of Kallikrein 15 is essential for developing targeted therapies and diagnostic tools for diseases where its involvement is critical. The Kallikrein 15 Polyclonal Antibody provides researchers with a reliable tool to further explore the role of this protein in health and disease.
Product Name:
KLK15 Rabbit Polyclonal Antibody
SKU:
CAB2757
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human KLK15 (NP_059979.2).
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In prostate cancer, this gene has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method:
Affinity purification
Gene ID:
55554
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KLK15 Rabbit pAb (CAB2757) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
