The KAL1 Polyclonal Antibody (CAB16389) is a valuable tool for researchers studying KAL1, a gene associated with Kallmann syndrome, a rare genetic disorder that affects the development of the reproductive system and sense of smell. This antibody, produced using rabbits, exhibits high specificity and sensitivity for human samples, making it suitable for use in various research applications such as Western blotting.KAL1, also known as Anosmin-1, plays a crucial role in the development of the olfactory and reproductive systems during embryonic development. Mutations in the KAL1 gene can lead to Kallmann syndrome, characterized by delayed or absent puberty and anosmia.
By using the KAL1 Polyclonal Antibody, researchers can study the expression and function of KAL1 in different cell types, providing insights into the mechanisms underlying Kallmann syndrome and potential therapeutic interventions.Overall, the KAL1 Polyclonal Antibody is a reliable tool for investigating the role of KAL1 in development and disease, offering researchers valuable insights into the molecular pathways involved in Kallmann syndrome and related conditions.
Product Name:
KAL1 Rabbit Polyclonal Antibody
SKU:
CAB16389
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human KAL1 (NP_000207.2).
Mutations in this gene cause the X-linked Kallmann syndrome. The encoded protein is similar in sequence to proteins known to function in neural cell adhesion and axonal migration. In addition, this cell surface protein is N-glycosylated and may have anti-protease activity.
Purification Method:
Affinity purification
Gene ID:
3730
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KAL1 Rabbit pAb (CAB16389) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
