K63-linkage Specific Polyubiquitin Rabbit Polyclonal Antibody (CAB18164)
- SKU:
- CAB18164
- Product Type:
- Antibody
- Reactivity:
- Universal
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | K63-linkage Specific Polyubiquitin Rabbit Polyclonal Antibody |
SKU: | CAB18164 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat,Other (Wide Range Predicted) |
Immunogen: | A synthetic peptide corresponding to a sequence containing polyubiquitinated protein (K63 linkage). |
Tested Applications: | ELISA DB |
Recommended Dilution: | DB,1:500 - 1:1000 |
Positive Sample: | HeLa,HeLa+MG132,NIH/3T3,C6,Mouse brain,Rat brain |
Observed MW: | 15-200kDa |
Ubiquitination,onetypeofthemostcommonpost-translationalmodification,mediatestheregulationofproteinhomeostasisinvivo.SinceubiquitinitselfcontainsmultiplelysineresiduesandoneN-terminalfreeaminogroup,eighttypesofubiquitinchainscanbeformed.? K63-linked polyubiquitin chains exert nonproteolytic functions in vivo, such as protein trafficking, kinase/phosphatase activation, and DNA damage control, all of which might be important in regulation of cancer survival and development (PMID: 19217402,PMCID: PMC3008764).
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |