K6-linkage Specific Polyubiquitin Rabbit Polyclonal Antibody (CAB18106)
- SKU:
- CAB18106
- Product Type:
- Antibody
- Reactivity:
- Universal
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | K6-linkage Specific Polyubiquitin Rabbit Polyclonal Antibody |
SKU: | CAB18106 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence containing polyubiquitinated protein (K6 linkage). |
Tested Applications: | WB ELISA DB |
Recommended Dilution: | WB,1:500 - 1:2000 DB,1:500 - 1:1000 |
Positive Sample: | RAW264.7,C6 |
Polyubiquitin chains regulate diverse cellular processes through the ability of ubiquitin to form chains of eight different linkage types. Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair. it has been reported that modification at Lys-6 inhibits ubiquitin-dependent protein degradation, a failure of the ubiquitin-proteasome system could play a role in initiating the formation of degradation-resistant PHF tangles.
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |