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JunD Rabbit Monoclonal Antibody (CAB5433)

SKU:
CAB5433
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:JunD Rabbit Monoclonal Antibody
SKU:CAB5433
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 100-200 of human JunD (P17535).
Sequence:SPEL ERLI IQSN GLVT TTPT SSQF LYPK VAAS EEQE FAEG FVKA LEDL HKQN QLGA GAAA AAAA AAAG GPSG TATG SAPP GELA PAAA APEA PVYA NLSS Y
Tested Applications:WB IP ChIP ELISA CUT&Tag
Recommended Dilution:WB,1:500 - 1:2000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cellsChIP,5μg antibody for 10μg-15μg of ChromatinCUT&Tag, 10⁵ cells /1 μg
Synonyms:AP-1; JunD
Positive Sample:HeLa,HT-1080
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:35kDa
Observed MW:38kDa/42kDa

The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216).

Purification Method:Affinity purification
Gene ID:3727
Clone Number:ARC1408
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageCUT&Tag was performed using the CUT&Tag Assay Kit (pAG-Tn5) for Illumina(RK20265) from 10⁵ Hep G2 cells with 1 μg JunD Rabbit mAb (CAB5433), along with a Goat Anti-Rabbit IgG(H+L). The CUT&Tag results indicate the enrichment pattern of JunD in representative gene loci (TP53INP2), as shown in figure.

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