The JUND Rabbit Monoclonal Antibody (CAB5433) is a cutting-edge tool for researchers investigating the JUND protein, a transcription factor involved in regulating gene expression and cell proliferation. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it an excellent choice for Western blot applications.The JUND protein is known for its role in various biological processes, including cell growth, differentiation, and apoptosis. It is also implicated in diseases such as cancer, where its dysregulation can promote tumor growth and metastasis. By targeting the JUND protein, researchers can gain insights into the molecular mechanisms underlying these conditions and potentially identify new therapeutic targets.
With its ability to specifically bind to the JUND protein, the CAB5433 antibody enables precise detection and analysis of JUND expression in different cell types. Its versatility and reliability make it an essential tool for studies in molecular biology, oncology, and drug discovery. By studying the function of JUND, researchers can advance our understanding of disease pathways and develop innovative strategies for diagnosis and treatment.
Product Name:
JunD Rabbit Monoclonal Antibody
SKU:
CAB5433
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human JunD (P17535).
WB,1:500 - 1:2000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cellsChIP,5μg antibody for 10μg-15μg of ChromatinCUT&Tag, 10⁵ cells /1 μg
Synonyms:
AP-1; JunD
Positive Sample:
HeLa,HT-1080
Conjugate:
Unconjugated
Cellular Localization:
Nucleus.
Calculated MW:
35kDa
Observed MW:
38kDa/42kDa
The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216).
Purification Method:
Affinity purification
Gene ID:
3727
Clone Number:
ARC1408
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
CUT&Tag was performed using the CUT&Tag Assay Kit (pAG-Tn5) for Illumina(RK20265) from 10⁵ Hep G2 cells with 1 μg JunD Rabbit mAb (CAB5433), along with a Goat Anti-Rabbit IgG(H+L). The CUT&Tag results indicate the enrichment pattern of JunD in representative gene loci (TP53INP2), as shown in figure.
