The JUND Polyclonal Antibody (CAB11955) is a crucial tool for researchers studying the JUND protein, a transcription factor involved in cellular processes such as proliferation, apoptosis, and immune response regulation. This antibody is produced in rabbits and is highly specific for detecting JUND in human samples, making it ideal for Western blot applications.JUND, a member of the AP-1 transcription factor family, plays a critical role in regulating gene expression in response to various stimuli. Its involvement in cell growth, differentiation, and survival makes it a key target for investigation in cancer research and immunology studies.
The JUND Polyclonal Antibody binds specifically to the JUND protein, allowing for accurate detection and analysis in a variety of cell types.By understanding the function and regulation of JUND, researchers can gain insights into how this transcription factor influences immune responses, cell cycle control, and tumorigenesis. The JUND Polyclonal Antibody provides a reliable tool for studying JUND-related pathways and processes, facilitating advancements in drug development and therapeutic strategies for diseases associated with dysregulated JUND activity.
Product Name:
JunD Rabbit Polyclonal Antibody
SKU:
CAB11955
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human JunD (NP_005345.3).
The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216).
Purification Method:
Affinity purification
Gene ID:
3727
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using JunD Rabbit pAb (CAB11955) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
