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JunB Transcription Factor Activity Assay

SKU:
TFAB00079
Product Type:
ELISA Kit
ELISA Type:
Transcription Factor Assay
Analytes:
JunB
Reactivity:
Human
Mouse
$719
Frequently bought together:

Description

system_update_altDatasheet

JunB Transcription Factor Activity Assay

The JunB Transcription Factor Activity Assay Kit is specifically designed for the sensitive and accurate detection of JunB transcription factor activity in various biological samples. This kit offers high specificity and precision, providing researchers with reliable and reproducible results for their experiments.JunB is a key transcription factor that plays a crucial role in regulating gene expression and cellular processes such as proliferation, differentiation, and apoptosis. Abnormalities in JunB activity have been implicated in various diseases, including cancer, inflammatory disorders, and immune dysfunction, highlighting the importance of studying JunB in biological research.

With its easy-to-use format and robust performance, the JunB Transcription Factor Activity Assay Kit is an essential tool for investigating the function of JunB in different cellular pathways and disease contexts. Researchers can confidently rely on this kit to accurately measure JunB activity and gain valuable insights into its role in health and disease.

Product Name:JunB Transcription Factor Activity Assay
Product Code:TFAB00079
Target:JunB
Reactivity:Human, Mouse
Sample Types:Nuclear or cell lysates

The Assay Genie JunB transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates

Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.

Assay Time:4.5 hours
Detection Method:Colorimetric 450 nm
Size:12 x 8-Well Microstrips
Storage:4°C for 6 months
UniProt Protein Function:JunB: Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'. Binds DNA as an homodimer or as an heterodimer with another member of the Jun/Fos family. Interacts with ITCH (via its WW domains). By growth factors. Belongs to the bZIP family. Jun subfamily.
UniProt Protein Details:

Protein type:Motility/polarity/chemotaxis; Transcription factor; Oncoprotein

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: chromatin; nuclear chromatin; nucleoplasm; transcription factor complex

Molecular Function:DNA binding; protein binding; transcription coactivator activity; transcription corepressor activity; transcription factor binding

Biological Process: cellular response to hormone stimulus; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cell differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of cell cycle; regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; response to cAMP; response to cytokine stimulus; response to drug; response to lipopolysaccharide; response to mechanical stimulus; response to radiation

UniProt Code:P17275
NCBI GenInfo Identifier:135304
NCBI Gene ID:3726
NCBI Accession:P17275.1
UniProt Secondary Accession:P17275,Q96GH3,
UniProt Related Accession:P17275
Molecular Weight:35,879 Da
NCBI Full Name:Transcription factor jun-B
NCBI Synonym Full Names:JunB proto-oncogene, AP-1 transcription factor subunit
NCBI Official Symbol:JUNB  
NCBI Official Synonym Symbols:AP-1  
NCBI Protein Information:transcription factor jun-B
UniProt Protein Name:Transcription factor jun-B
Protein Family:Transcription factor
UniProt Gene Name:JUNB  
UniProt Entry Name:JUNB_HUMAN
AntibodiesELISA Kits
Anti-JUNB Antibody (CAB14566)JunB (Phospho-Ser259) Transcription Factor Activity Assay
Anti-JUNB Antibody (CAB4848)
Anti-JUNB Antibody (CAB5290)
Anti-Phospho-JUNB-S259 Antibody (CABP0375)
Anti-Phospho-JUNB-S79 Antibody (CABP0376)

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