The JUNB Polyclonal Antibody (CAB14566) is a valuable tool for research involving the JUNB protein, a transcription factor that plays a key role in cell growth, differentiation, and immune response regulation. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.JUNB is known to be involved in multiple cellular processes, including cell proliferation, apoptosis, and immune cell activation. Its dysregulation has been implicated in various diseases, including cancer, inflammatory disorders, and autoimmune conditions.
By targeting JUNB with this polyclonal antibody, researchers can effectively detect and analyze the protein in different cell types, providing insights into its function and potential therapeutic implications.Studies utilizing the JUNB Polyclonal Antibody are instrumental in advancing our understanding of the molecular mechanisms underlying diseases related to JUNB dysregulation. By elucidating the role of JUNB in immune modulation and cellular function, this antibody contributes to the development of targeted therapies aimed at manipulating JUNB activity for therapeutic benefit.
Product Name:
JunB Rabbit Polyclonal Antibody
SKU:
CAB14566
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human JunB (NP_002220.1).
Enables sequence-specific double-stranded DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in nucleoplasm. Part of transcription factor AP-1 complex. Biomarker of Hodgkin's lymphoma and anaplastic large cell lymphoma.
Purification Method:
Affinity purification
Gene ID:
3726
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using JunB Rabbit pAb (CAB14566) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
