The JUN Polyclonal Antibody (CAB16905) is a research tool designed for the detection and analysis of the JUN protein, a transcription factor that plays a key role in cell proliferation, differentiation, and apoptosis. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it suitable for use in Western blot applications.JUN is a critical regulator of gene expression and is involved in various cellular processes, including growth, development, and stress response. Its dysregulation has been implicated in diseases such as cancer, making it a valuable target for research in oncology and other fields.
Researchers studying JUN can utilize this antibody to explore its function in different cell types and conditions, allowing for a better understanding of its role in cellular processes and disease development. Overall, the JUN Polyclonal Antibody is a reliable tool for immunology and cancer research, providing valuable insights into the mechanisms underlying cellular function and disease progression.
Product Name:
c-Jun Rabbit Polyclonal Antibody
SKU:
CAB16905
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human c-Jun (NP_002219.1).
This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.
Purification Method:
Affinity purification
Gene ID:
3725
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from MCF7 cells, using c-Jun Rabbit pAb (CAB16905) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.